A Stereotactic Device for Intraparenchymal Spinal Cord Injections: Latest Developments for Practical Clinical Use

Thais Federici; Nathan Hardcastle; Pavlos Texakalidis; Muhibullah S. Tora; Jeremy Wetzel; Jonathan P. Riley; Nicholas M. Boulis

doi:10.1159/000512504

A Stereotactic Device for Intraparenchymal Spinal Cord Injections: Latest Developments for Practical Clinical Use

Thais Federici
, Nathan Hardcastle
, Pavlos Texakalidis
, Muhibullah S. Tora
, Jeremy Wetzel
, Jonathan P. Riley
, Nicholas M. Boulis

Neurosurgery

Emory University
Georgia Institute of Technology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

This manuscript introduces the latest generation of a patient-mounted platform designed for segmental injections of therapeutics direct into the spinal cord parenchyma. It emphasizes its importance and it presents the rationale for developing this delivery methodology. It compares the newest with the previous generations, detailing how the modifications can streamline transportation, assembly, sterilization, and utilization of the platform by different surgeons. Finally, the illustrations depict the main alterations, as well as a cadaveric assessment of the device prototype in the cervical and thoracolumbar regions.

Original language	English
Pages (from-to)	322-328
Number of pages	7
Journal	Stereotactic and Functional Neurosurgery
Volume	99
Issue number	4
DOIs	https://doi.org/10.1159/000512504
State	Published - Jul 1 2021

Keywords

Delivery
Device
Parenchyma
Platform
Spinal cord

Access to Document

10.1159/000512504

Cite this

@article{d58330c301bb40fa9e636f24a8bc93e0,

title = "A Stereotactic Device for Intraparenchymal Spinal Cord Injections: Latest Developments for Practical Clinical Use",

abstract = "This manuscript introduces the latest generation of a patient-mounted platform designed for segmental injections of therapeutics direct into the spinal cord parenchyma. It emphasizes its importance and it presents the rationale for developing this delivery methodology. It compares the newest with the previous generations, detailing how the modifications can streamline transportation, assembly, sterilization, and utilization of the platform by different surgeons. Finally, the illustrations depict the main alterations, as well as a cadaveric assessment of the device prototype in the cervical and thoracolumbar regions.",

keywords = "Delivery, Device, Parenchyma, Platform, Spinal cord",

author = "Thais Federici and Nathan Hardcastle and Pavlos Texakalidis and Tora, \{Muhibullah S.\} and Jeremy Wetzel and Riley, \{Jonathan P.\} and Boulis, \{Nicholas M.\}",

year = "2021",

month = jul,

day = "1",

doi = "10.1159/000512504",

language = "English",

volume = "99",

pages = "322--328",

journal = "Stereotactic and Functional Neurosurgery",

issn = "1011-6125",

publisher = "S. Karger AG",

number = "4",

}

TY - JOUR

T1 - A Stereotactic Device for Intraparenchymal Spinal Cord Injections

T2 - Latest Developments for Practical Clinical Use

AU - Federici, Thais

AU - Hardcastle, Nathan

AU - Texakalidis, Pavlos

AU - Tora, Muhibullah S.

AU - Wetzel, Jeremy

AU - Riley, Jonathan P.

AU - Boulis, Nicholas M.

PY - 2021/7/1

Y1 - 2021/7/1

N2 - This manuscript introduces the latest generation of a patient-mounted platform designed for segmental injections of therapeutics direct into the spinal cord parenchyma. It emphasizes its importance and it presents the rationale for developing this delivery methodology. It compares the newest with the previous generations, detailing how the modifications can streamline transportation, assembly, sterilization, and utilization of the platform by different surgeons. Finally, the illustrations depict the main alterations, as well as a cadaveric assessment of the device prototype in the cervical and thoracolumbar regions.

AB - This manuscript introduces the latest generation of a patient-mounted platform designed for segmental injections of therapeutics direct into the spinal cord parenchyma. It emphasizes its importance and it presents the rationale for developing this delivery methodology. It compares the newest with the previous generations, detailing how the modifications can streamline transportation, assembly, sterilization, and utilization of the platform by different surgeons. Finally, the illustrations depict the main alterations, as well as a cadaveric assessment of the device prototype in the cervical and thoracolumbar regions.

KW - Delivery

KW - Device

KW - Parenchyma

KW - Platform

KW - Spinal cord

UR - https://www.scopus.com/pages/publications/85102124835

U2 - 10.1159/000512504

DO - 10.1159/000512504

M3 - Article

C2 - 33657550

AN - SCOPUS:85102124835

SN - 1011-6125

VL - 99

SP - 322

EP - 328

JO - Stereotactic and Functional Neurosurgery

JF - Stereotactic and Functional Neurosurgery

IS - 4

ER -

A Stereotactic Device for Intraparenchymal Spinal Cord Injections: Latest Developments for Practical Clinical Use

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this