A rapid and simple cleanup procedure for metathesis reactions

Brandon R. Galan; Kyle P. Kalbarczyk; Steven Szczepankiewicz; Jerome B. Keister; Steven T. Diver

doi:10.1021/ol0631399

A rapid and simple cleanup procedure for metathesis reactions

Brandon R. Galan
, Kyle P. Kalbarczyk
, Steven Szczepankiewicz
, Jerome B. Keister
, Steven T. Diver

Chemistry

SUNY Buffalo
Canisius College

Research output: Contribution to journal › Article › peer-review

129 Scopus citations

Abstract

Figure presented A new method for easy removal of ruthenium from metathesis reactions by using a polar isocyanide is reported. This protocol removed most ruthenium byproducts from a variety of synthetically useful metatheses. Moreover, the isocyanide-promoted carbene insertion results in rapid destruction of carbene reactivity, demonstrated in the commonly used first- and second-generation Grubbs' carbenes.

Original language	English
Pages (from-to)	1203-1206
Number of pages	4
Journal	Organic Letters
Volume	9
Issue number	7
DOIs	https://doi.org/10.1021/ol0631399
State	Published - Mar 29 2007

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10.1021/ol0631399

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title = "A rapid and simple cleanup procedure for metathesis reactions",

abstract = "Figure presented A new method for easy removal of ruthenium from metathesis reactions by using a polar isocyanide is reported. This protocol removed most ruthenium byproducts from a variety of synthetically useful metatheses. Moreover, the isocyanide-promoted carbene insertion results in rapid destruction of carbene reactivity, demonstrated in the commonly used first- and second-generation Grubbs' carbenes.",

author = "Galan, \{Brandon R.\} and Kalbarczyk, \{Kyle P.\} and Steven Szczepankiewicz and Keister, \{Jerome B.\} and Diver, \{Steven T.\}",

year = "2007",

month = mar,

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doi = "10.1021/ol0631399",

language = "English",

volume = "9",

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journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

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T1 - A rapid and simple cleanup procedure for metathesis reactions

AU - Galan, Brandon R.

AU - Kalbarczyk, Kyle P.

AU - Szczepankiewicz, Steven

AU - Keister, Jerome B.

AU - Diver, Steven T.

PY - 2007/3/29

Y1 - 2007/3/29

N2 - Figure presented A new method for easy removal of ruthenium from metathesis reactions by using a polar isocyanide is reported. This protocol removed most ruthenium byproducts from a variety of synthetically useful metatheses. Moreover, the isocyanide-promoted carbene insertion results in rapid destruction of carbene reactivity, demonstrated in the commonly used first- and second-generation Grubbs' carbenes.

AB - Figure presented A new method for easy removal of ruthenium from metathesis reactions by using a polar isocyanide is reported. This protocol removed most ruthenium byproducts from a variety of synthetically useful metatheses. Moreover, the isocyanide-promoted carbene insertion results in rapid destruction of carbene reactivity, demonstrated in the commonly used first- and second-generation Grubbs' carbenes.

UR - https://www.scopus.com/pages/publications/34147157753

U2 - 10.1021/ol0631399

DO - 10.1021/ol0631399

M3 - Article

AN - SCOPUS:34147157753

SN - 1523-7060

VL - 9

SP - 1203

EP - 1206

JO - Organic Letters

JF - Organic Letters

IS - 7

ER -

A rapid and simple cleanup procedure for metathesis reactions

Abstract

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