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A possible role for glucocorticoids in denervation atrophy

  • SUNY Buffalo

Research output: Contribution to journalArticlepeer-review

108 Scopus citations

Abstract

Skeletal muscle atrophies after denervation. Glucocorticoids also cause skeletal muscle to atrophy. The data presented in this report demonstrate that after denervation there is a significant increase in the number of glucocorticoid receptors in the cytosol of skeletal muscle of rats. The results are consistent with the hypothesis that a skeletal muscle atrophies after denervation because it becomes hypersensitive to glucocorticoids.

Original languageEnglish
Pages (from-to)370-373
Number of pages4
JournalMuscle and Nerve
Volume4
Issue number5
DOIs
StatePublished - 1981

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