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A one-pot method for the efficient preparation of aromatic nitriles from aldehydes using ammonia, magnesium sulfate, and manganese dioxide

  • SUNY Buffalo

Research output: Contribution to journalArticlepeer-review

47 Scopus citations

Abstract

A one-pot and efficient preparation of aromatic nitriles from the corresponding aldehydes was accomplished by treatment with 2 M ammonia solution in 2-propanol, magnesium sulfate, and manganese dioxide in THF at room temperature. This method was found to be compatible with a variety of functionalities such as hydroxyl, ester, and amide.

Original languageEnglish
Pages (from-to)230-231
Number of pages2
JournalSynlett
Issue number2
DOIs
StatePublished - 2001

Keywords

  • Aldehydes
  • Aromatic nitriles
  • Manganese dioxide

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