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A numerical model for the trans-membrane voltage of vesicles

  • SUNY Buffalo

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The Immersed Interface Method is employed to solve the time-varying electric field equations around a three-dimensional vesicle. To achieve second-order accuracy the implicit jump conditions for the electric potential, up to the second normal derivative, are derived. The trans-membrane potential is determined implicitly as part of the algorithm. The method is compared to an analytic solution based on spherical harmonics and verifies the second-order accuracy of the underlying discretization even in the presence of solution discontinuities. A sample result for an elliptic interface is also presented.

Original languageEnglish
Pages (from-to)7-12
Number of pages6
JournalApplied Mathematics Letters
Volume39
DOIs
StatePublished - Jan 2015

Keywords

  • Electric field
  • Immersed interface method
  • Trans-membrane potential
  • Vesicle

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