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A hybrid registration approach for matching genomic structures in multimodal microscopic images of living cells

  • Fayetteville State University
  • Pennsylvania State University
  • SUNY Buffalo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

5 Scopus citations

Abstract

A new registration approach is presented for matching genomic structures in time lapse microscopy images of living cells which have been labeled with fluorescent protein. Registration of microscopic images is a difficult problem due to signal weakness and low resolution of structures of interest. With this in mind we have developed a hybrid approach that matches two time point images by deformation based on corresponding control points from two different microscopic modalities. This approach is robust because it can also be initialized by the point correspondences established by our previously published method [2-3]. We discuss several choices for the deformation technique and present experimental results which rank them on accuracy as evaluated by an expert user.

Original languageEnglish
Title of host publicationProceedings of the 2008 International Conference on Image Processing, Computer Vision, and Pattern Recognition, IPCV 2008
Pages217-221
Number of pages5
StatePublished - 2008
Event2008 International Conference on Image Processing, Computer Vision, and Pattern Recognition, IPCV 2008 - Las Vegas, NV, United States
Duration: Jul 14 2008Jul 17 2008

Publication series

NameProceedings of the 2008 International Conference on Image Processing, Computer Vision, and Pattern Recognition, IPCV 2008

Conference

Conference2008 International Conference on Image Processing, Computer Vision, and Pattern Recognition, IPCV 2008
Country/TerritoryUnited States
CityLas Vegas, NV
Period07/14/0807/17/08

Keywords

  • Biological living cells
  • Feature extraction
  • Image registration
  • Microscopy

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