A highly tunable biocompatible and multifunctional biodegradable elastomer

Maria José Nunes Pereira; Ben Ouyang; Cathryn A. Sundback; Nora Lang; Ingeborg Friehs; Shwetha Mureli; Irina Pomerantseva; Jacob McFadden; Mark C. Mochel; Olive Mwizerwa; Pedro Del Nido; Debanjan Sarkar; Peter T. Masiakos; Robert Langer; Lino S. Ferreira; Jeffrey M. Karp

doi:10.1002/adma.201203824

A highly tunable biocompatible and multifunctional biodegradable elastomer

Maria José Nunes Pereira
, Ben Ouyang
, Cathryn A. Sundback
, Nora Lang
, Ingeborg Friehs
, Shwetha Mureli
, Irina Pomerantseva
, Jacob McFadden
, Mark C. Mochel
, Olive Mwizerwa
, Pedro Del Nido
, Debanjan Sarkar
, Peter T. Masiakos
, Robert Langer
, Lino S. Ferreira
, Jeffrey M. Karp

Department of Biomedical Engineering

Brigham and Women’s Hospital
University of Coimbra
Harvard University
Boston Children's Hospital
Massachusetts General Hospital
Massachusetts Institute of Technology

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Abstract

Biodegradable elastomers synthesized under mild conditions with highly tunable mechanical properties are described. These elastomeric biomaterials are biocompatible, exhibit minimal deformation following cyclical tensile loading, and permit tight control over the release kinetics of encapsulated bioactive molecules.

Original language	English
Pages (from-to)	1209-1215
Number of pages	7
Journal	Advanced Materials
Volume	25
Issue number	8
DOIs	https://doi.org/10.1002/adma.201203824
State	Published - Feb 25 2013

Keywords

biocompatible materials
biodegradable polymers
biomacromolecules
drug delivery
elastomers

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10.1002/adma.201203824

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Pereira, M. J. N., Ouyang, B., Sundback, C. A., Lang, N., Friehs, I., Mureli, S., Pomerantseva, I., McFadden, J., Mochel, M. C., Mwizerwa, O., Del Nido, P., Sarkar, D., Masiakos, P. T., Langer, R., Ferreira, L. S., & Karp, J. M. (2013). A highly tunable biocompatible and multifunctional biodegradable elastomer. Advanced Materials, 25(8), 1209-1215. https://doi.org/10.1002/adma.201203824

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title = "A highly tunable biocompatible and multifunctional biodegradable elastomer",

abstract = "Biodegradable elastomers synthesized under mild conditions with highly tunable mechanical properties are described. These elastomeric biomaterials are biocompatible, exhibit minimal deformation following cyclical tensile loading, and permit tight control over the release kinetics of encapsulated bioactive molecules.",

keywords = "biocompatible materials, biodegradable polymers, biomacromolecules, drug delivery, elastomers",

author = "Pereira, \{Maria Jos{\'e} Nunes\} and Ben Ouyang and Sundback, \{Cathryn A.\} and Nora Lang and Ingeborg Friehs and Shwetha Mureli and Irina Pomerantseva and Jacob McFadden and Mochel, \{Mark C.\} and Olive Mwizerwa and \{Del Nido\}, Pedro and Debanjan Sarkar and Masiakos, \{Peter T.\} and Robert Langer and Ferreira, \{Lino S.\} and Karp, \{Jeffrey M.\}",

year = "2013",

month = feb,

day = "25",

doi = "10.1002/adma.201203824",

language = "English",

volume = "25",

pages = "1209--1215",

journal = "Advanced Materials",

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publisher = "Wiley-Blackwell",

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Pereira, MJN, Ouyang, B, Sundback, CA, Lang, N, Friehs, I, Mureli, S, Pomerantseva, I, McFadden, J, Mochel, MC, Mwizerwa, O, Del Nido, P, Sarkar, D, Masiakos, PT, Langer, R, Ferreira, LS & Karp, JM 2013, 'A highly tunable biocompatible and multifunctional biodegradable elastomer', Advanced Materials, vol. 25, no. 8, pp. 1209-1215. https://doi.org/10.1002/adma.201203824

TY - JOUR

T1 - A highly tunable biocompatible and multifunctional biodegradable elastomer

AU - Pereira, Maria José Nunes

AU - Ouyang, Ben

AU - Sundback, Cathryn A.

AU - Lang, Nora

AU - Friehs, Ingeborg

AU - Mureli, Shwetha

AU - Pomerantseva, Irina

AU - McFadden, Jacob

AU - Mochel, Mark C.

AU - Mwizerwa, Olive

AU - Del Nido, Pedro

AU - Sarkar, Debanjan

AU - Masiakos, Peter T.

AU - Langer, Robert

AU - Ferreira, Lino S.

AU - Karp, Jeffrey M.

PY - 2013/2/25

Y1 - 2013/2/25

N2 - Biodegradable elastomers synthesized under mild conditions with highly tunable mechanical properties are described. These elastomeric biomaterials are biocompatible, exhibit minimal deformation following cyclical tensile loading, and permit tight control over the release kinetics of encapsulated bioactive molecules.

AB - Biodegradable elastomers synthesized under mild conditions with highly tunable mechanical properties are described. These elastomeric biomaterials are biocompatible, exhibit minimal deformation following cyclical tensile loading, and permit tight control over the release kinetics of encapsulated bioactive molecules.

KW - biocompatible materials

KW - biodegradable polymers

KW - biomacromolecules

KW - drug delivery

KW - elastomers

UR - https://www.scopus.com/pages/publications/84874103151

U2 - 10.1002/adma.201203824

DO - 10.1002/adma.201203824

M3 - Article

C2 - 23239051

AN - SCOPUS:84874103151

SN - 0935-9648

VL - 25

SP - 1209

EP - 1215

JO - Advanced Materials

JF - Advanced Materials

IS - 8

ER -

A highly tunable biocompatible and multifunctional biodegradable elastomer

Abstract

Keywords

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