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A gene controlling bell and photically induced ovulation in mice

  • Jackson Laboratory

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Virgin female mice of two unrelated, highly inbred strains, BALB/cBy and C57CL/6By, seven of their derived recombinant inbred strains, and their F1 hybrid generations, were exposed either to an intermittently ringing bell or to a flashing, high intensity light. The females were treated, before exposure, with 1.5 i.u. PMSG. After exposure, the number of ova per treated or per responding female and the percentage of responding females were counted. The matching strain distribution pattern and the test of a congenic line permitted characterization of a gene exerting a major effect on bell or flash induced ovulation. The gene is located in Chromosome 4 (LG VIII). The symbol Bfo is proposed. One or more additional loci appeared to be involved and possibly interaction between loci.

Original languageEnglish
Pages (from-to)41-47
Number of pages7
JournalJournal of Reproduction and Fertility
Volume38
Issue number1
DOIs
StatePublished - 1974

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