A convenient synthesis of lacto-N-biose I [β-d-Galp-(1 → 3)-β-d-GlcpNAc] linked oligosaccharides from phenyl O-(tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside

Rakesh K. Jain; Robert D. Locke; Khushi L. Matta

doi:10.1016/0008-6215(93)80103-L

A convenient synthesis of lacto-N-biose I [β-d-Galp-(1 → 3)-β-d-GlcpNAc] linked oligosaccharides from phenyl O-(tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside

Rakesh K. Jain
, Robert D. Locke
, Khushi L. Matta

Department of Chemical and Biological Engineering

Roswell Park Cancer Institute

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The synthesis of two tetrasaccharides and one trisaccharide containing lacto-N-biose I (β-d-Galp-(1 → 3)-β-d-GlcpNAc) as their terminal unit was accomplished through development and utilization of a key glycosyl donor, namely, phenyl O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside.

Original language	English
Pages (from-to)	165-176
Number of pages	12
Journal	Carbohydrate Research
Volume	241
Issue number	C
DOIs	https://doi.org/10.1016/0008-6215(93)80103-L
State	Published - Mar 17 1993

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@article{530cfbbf27fa456694dcd4c8d5593a06,

title = "A convenient synthesis of lacto-N-biose I [β-d-Galp-(1 → 3)-β-d-GlcpNAc] linked oligosaccharides from phenyl O-(tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside",

abstract = "The synthesis of two tetrasaccharides and one trisaccharide containing lacto-N-biose I (β-d-Galp-(1 → 3)-β-d-GlcpNAc) as their terminal unit was accomplished through development and utilization of a key glycosyl donor, namely, phenyl O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside.",

author = "Jain, \{Rakesh K.\} and Locke, \{Robert D.\} and Matta, \{Khushi L.\}",

year = "1993",

month = mar,

day = "17",

doi = "10.1016/0008-6215(93)80103-L",

language = "English",

volume = "241",

pages = "165--176",

journal = "Carbohydrate Research",

issn = "0008-6215",

publisher = "Elsevier Ltd",

number = "C",

}

A convenient synthesis of lacto-N-biose I [β-d-Galp-(1 → 3)-β-d-GlcpNAc] linked oligosaccharides from phenyl O-(tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside. / Jain, Rakesh K.; Locke, Robert D.; Matta, Khushi L.
In: Carbohydrate Research, Vol. 241, No. C, 17.03.1993, p. 165-176.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - A convenient synthesis of lacto-N-biose I [β-d-Galp-(1 → 3)-β-d-GlcpNAc] linked oligosaccharides from phenyl O-(tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside

AU - Jain, Rakesh K.

AU - Locke, Robert D.

AU - Matta, Khushi L.

PY - 1993/3/17

Y1 - 1993/3/17

N2 - The synthesis of two tetrasaccharides and one trisaccharide containing lacto-N-biose I (β-d-Galp-(1 → 3)-β-d-GlcpNAc) as their terminal unit was accomplished through development and utilization of a key glycosyl donor, namely, phenyl O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside.

AB - The synthesis of two tetrasaccharides and one trisaccharide containing lacto-N-biose I (β-d-Galp-(1 → 3)-β-d-GlcpNAc) as their terminal unit was accomplished through development and utilization of a key glycosyl donor, namely, phenyl O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside.

UR - https://www.scopus.com/pages/publications/0027572048

U2 - 10.1016/0008-6215(93)80103-L

DO - 10.1016/0008-6215(93)80103-L

M3 - Article

C2 - 8472252

AN - SCOPUS:0027572048

SN - 0008-6215

VL - 241

SP - 165

EP - 176

JO - Carbohydrate Research

JF - Carbohydrate Research

IS - C

ER -

A convenient synthesis of lacto-N-biose I [β-d-Galp-(1 → 3)-β-d-GlcpNAc] linked oligosaccharides from phenyl O-(tetra-O-acetyl-β-d-galactopyranosyl)-(1 → 3)-4,6-di-O-acetyl-2-deoxy-2-phthalimido-1-thio-β-d-glucopyranoside

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