利用LIBS技术区分皮内痣组织与真皮组织

In laser nevus removal surgery, doctors rely on naked eyes to judge the boundary between the nevus and normal tissue, which leads to incomplete clearance of nevus tissue and recurrence in a large number of cases. We use laser-induced breakdown spectroscopy to provide real-time feedback on the spectral information of the tissue in the process of laser removal of nevus so as to eliminate the nevus completely and avoid recurrence after operation. We use four groups of the patients' surgical removed intradermal nevus and dermal tissues as subjects and establish the mathematical model by using the characteristic peaks of both Ca at 393.4 nm and 396.8 nm and Na at 589.0 nm and 589.6 nm via atomic emission spectroscopy. According to our model, the success rate of distinguishing intradermal nevus from dermal tissue reaches 97.5%.