BMP's Regulate Ionotropic Glutamate Receptors

Bone morphogenetic proteins (BMPs) regulate many aspects of neural development and they are also neuroprotective in mature animals. It is, therefore, important to understand the mechanism of action of these neurotrophic factors. Previous studies of BMP signaling pathways have focused on the transcriptional activities of these proteins and have emphasized their ability to alter neural cell fate by inducing or repressing gene expression. Preliminary studies from this laboratory, however, indicate that BMPs can also induce rapid (