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Collaborations and top research areas from the last five years
Grants & Projects
- 22 Finished
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Improving proteasome function to treat Charcot Marie Tooth 1A and 1B
Wrabetz, L. (CoI) & Feltri, M. (PI)
Charcot-Marie-Tooth Association
05/1/21 → 06/30/23
Project: Research
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FELLOWSHIP for Michael Weaver: Strn3 is a novel Rac1 effector in Schwann cells
Sigurdson, W. (CoI), Silvestri, N. (CoI), Wrabetz, L. (CoI) & Feltri, M. (PI)
National Inst of Neurological Disorders & Stroke
08/1/20 → 06/30/21
Project: Research
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Mechanisms of axonal degeneration in late onset CMT1B neuropathy: molecular pathways and therapeutic approaches
Wrabetz, L. (PI) & Feltri, M. (CoI)
Charcot-Marie-Tooth Association
12/1/19 → 11/30/21
Project: Research
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Selective galactosylceramidase ablation to study the pathogenesis of Krabbe leukodystrophy
Shin, D. (PI), Wrabetz, L. (CoI) & Feltri, M. (CoI)
National Inst of Neurological Disorders & Stroke
12/1/19 → 11/30/24
Project: Research
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The Peripheral Nervous System: A Window Into Krabbe Disease
Sim, F. (PI), Paez, P. (CoI), Qu, J. (CoI), Shin, D. (CoI), Wrabetz, L. (CoI) & Feltri, M. (PI)
National Inst of Neurological Disorders & Stroke
02/1/19 → 01/31/25
Project: Research
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Macrophage Targeting Protects Nerve Structure and Improves Muscle Innervation in a Mouse Model of Charcot-Marie-Tooth 2J
Klein, D., Ercan, N., Yuan, X., Shackleford, G. G., Claessens, A., Feltri, M. L., Wrabetz, L., D'Antonio, M. & Martini, R., Dec 2025, In: GLIA. 73, 12, p. 2369-2385 17 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Knockout of PA200 improves proteasomal degradation and myelination in a proteotoxic neuropathy
Verplank, J. J. S., Gawron, J. M., Silvestri, N. J., Wrabetz, L. & Feltri, M. L., Apr 2024, In: Life Science Alliance. 7, 4, e202302349.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination
Wilson, E. R., Nunes, G. D. F., Shen, S., Moore, S., Gawron, J., Maxwell, J., Syed, U., Hurley, E., Lanka, M., Qu, J., Désaubry, L., Wrabetz, L., Poitelon, Y. & Feltri, M. L., Dec 2024, In: GLIA. 72, 12, p. 2247-2267 21 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
P38γMAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions
Marziali, L. N., Hwang, Y., Palmisano, M., Cuenda, A., Sim, F. J., Gonzalez, A., Volsko, C., Dutta, R., Trapp, B. D., Wrabetz, L. & Feltri, M. L., May 1 2024, In: Brain. 147, 5, p. 1871-1886 16 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication
Shackleford, G. G., Marziali, L. N., Sasaki, Y., Claessens, A., Ferri, C., Weinstock, N. I., Rossor, A. M., Silvestri, N. J., Wilson, E. R., Hurley, E., Kidd, G. J., Manohar, S., Ding, D., Salvi, R. J., Laura Feltri, M., D’Antonio, M. & Wrabetz, L., Nov 9 2022, In: PLOS Genetics. 18, 11, e1010477.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations