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Collaborations and top research areas from the last five years
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Studies on Enzyme Activation
Richard, J. (PI)
National Institute of General Medical Sciences
08/15/25 → 07/31/28
Project: Research
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Studies on Enzyme Activation and Novel Modes of Inhibition
Richard, J. (PI)
National Institute of General Medical Sciences
01/1/20 → 08/14/25
Project: Research
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Activation of Enzymes for Catalysis: The Role of Substrate-Induced Structural Changes
Richard, J. (PI) & Amyes, T. (CoI)
National Institute of General Medical Sciences
12/21/15 → 12/31/20
Project: Research
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MRI: Acquisition of a 600 MHz NMR console
Szyperski, T. (PI), Gong, B. (CoI), Morrow, J. (CoI), Richard, J. (CoI) & Sukumaran, D. (CoI)
09/1/12 → 08/31/13
Project: Research
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Reactive Intermediates of Enzymatic Reactions
Richard, J. (PI)
National Institute of General Medical Sciences
05/1/09 → 08/31/14
Project: Research
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Bill Jencks’ Model for Lifetime Enforced Changes in Reaction Mechanism: A Legacy for Physical Organic Chemistry
Richard, J. P., Oct 15 2025, In: ChemPhysChem. 26, 20, e202500283.Research output: Contribution to journal › Article › peer-review
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Enzyme Architecture: Activation of Phosphite Dehydrogenase-Catalyzed Hydride Transfer by NAD+ Cofactor Fragments
Hegazy, R. & Richard, J. P., Dec 2 2025, In: Biochemistry. 64, 23, p. 4581-4593 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
The Role of Protein Side Chains in Enzyme-Activating Conformational Changes: Lessons from Studies on Variant Enzymes
Hegazy, R. & Richard, J. P., Dec 10 2025, In: Chemical Reviews. 125, 23, p. 11524-11566 43 p.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
Changes in mechanism and transition state structure for solvolysis reactions of ring substituted benzyl chlorides in aqueous solution
Yeary, P. E. & Richard, J. P., Jul 2024, In: Journal of Physical Organic Chemistry. 37, 7, e4600.Research output: Contribution to journal › Article › peer-review
Open Access -
Glycerol 3-Phosphate Dehydrogenase: Role of the Protein Conformational Change in Activation of a Readily Reversible Enzyme-Catalyzed Hydride Transfer Reaction
Cristobal, J. R., Hegazy, R. & Richard, J. P., Apr 16 2024, In: Biochemistry. 63, 8, p. 1016-1025 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations