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Collaborations and top research areas from the last five years
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(For Jamie Abbott) Positive Allosteric Modulation of NMDA Receptors in Treatment of Schizophrenia
Popescu, G. (PI)
Brain and Behavior Research Foundation
01/15/26 → 01/14/28
Project: Research
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Fellowship for S. Schwarz: Mechanism of Altered Synaptic Signaling by Disease Related GRIN1 Variants
Popescu, G. (PI) & Haj-Dahmane, S. (PI)
National Inst of Neurological Disorders & Stroke
03/26/25 → 03/25/27
Project: Research
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CTSA UM1 State University of New York at Buffalo
Murphy, T. (PI), Sethi, S. (PI), Benedict, R. (CoI), Bisson, L. (CoI), Cadzow, R. (CoI), Cavuoto, L. (CoI), Ceusters, W. (CoI), Chakraborty, S. (CoI), Chandrasekharan, P. (CoI), Chang, Y.-P. (CoI), Daly, C. (CoI), Diehl, A. (CoI), Epstein, L. (CoI), Falls, Z. (CoI), Franklin, G. (CoI), Gao, M. (CoI), Halterman, M. (CoI), Hu, J. (CoI), Jacobs, D. (CoI), Kayler, L. (CoI), Lackner, J. (CoI), Lamonte, M. (CoI), Lillvis, D. (CoI), Liu, X. (CoI), Miecznikowski, J. (CoI), Morse, E. (CoI), Noyes, E. (CoI), Popescu, G. (CoI), Prescott, G. (CoI), Quattrin, T. (CoI), Russo, T. (CoI), Samudrala, V. (CoI), Singh, R. (CoI), Surtees, J. (CoI), Szigeti, K. (CoI), Titus, A. (CoI), Tornatore-Morse, K. (CoI), Tumiel-Berhalter, L. (CoI), Vest, B. (CoI), Wilding, G. (CoI), Williams, J. (CoI), Winkelstein, P. (CoI), Xiong, J. (CoI), Zola, J. (CoI), Lokhande, V. (CoI), Rogers, A. (CoI) & Baumgartner, A. (CoI)
National Center for Advancing Translational Sciences
01/1/25 → 12/31/31
Project: Research
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Molecular Physiology of NMDA Receptors
Popescu, G. (PI)
National Inst of Neurological Disorders & Stroke
05/1/23 → 04/30/31
Project: Research
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Experience-Dependent Reorganization of Excitatory Synapse Connectivity
Popescu, G. (PI)
National Institute of Mental Health
02/2/22 → 05/31/25
Project: Research
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Distinct allosteric paths mediate a Ca2+-dependent increase in NMDA receptor sensitivity to open-channel blockers
Weaver, M. G., Abbott, J. A. & Popescu, G. K., Mar 17 2026, In: Biophysical Journal. 125, 6, p. 1456-1463 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The positive allosteric modulator GNE-9278 increases gating, conductance, and Ca2+ permeability for GluN2D-containing NMDA receptors
Abbott, J. A., Weaver, M. G., Liu, B., Schwarz, S. R. & Popescu, G. K., Jul 2026, In: Neuropsychopharmacology. 51, 8, p. 1395-1401 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Allosteric inhibition of NMDA receptors by low dose ketamine
Abbott, J. A., Wen, H., Liu, B., Gupta, S. S., Iacobucci, G. J., Zheng, W. & Popescu, G. K., Mar 2025, In: Molecular Psychiatry. 30, 3, p. 1009-1018 10 p., 4114.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements
Abbott, J. A., Kim, J., Liu, B., Popescu, G. K., Gouaux, E. & Jalali-Yazdi, F., Sep 24 2025, In: Science Advances. 11, 39, eadx4647.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Dynamic control of NMDA receptor Ca2+ permeability by endogenous and synthetic modulators
Weaver, M. G. & Popescu, G. K., Oct 21 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 42, e2511783122.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations