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Daniel Gewirth

    1984 …2025

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    • Selective Inhibition of hsp90 Paralogs: Uncovering the Role of Helix 1 in Grp94-Selective Ligand Binding

      Que, N. L. S., Seidler, P. M., Aw, W. J., Chiosis, G. & Gewirth, D. T., Mar 2025, In: Proteins: Structure, Function and Bioinformatics. 93, 3, p. 654-672 19 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      4 Scopus citations

    • Second international symposium on the chaperone code, 2023

      Buchner, J., Alasady, M. J., Backe, S. J., Blagg, B. S. J., Carpenter, R. L., Colombo, G., Gelis, I., Gewirth, D. T., Gierasch, L. M., Houry, W. A., Johnson, J. L., Kang, B. H., Kao, A. W., LaPointe, P., Mattoo, S., McClellan, A. J., Neckers, L. M., Prodromou, C., Rasola, A. & Sager, R. A. & 7 others, Theodoraki, M. A., Truman, A. W., Truttman, M. C., Zachara, N. E., Bourboulia, D., Mollapour, M. & Woodford, M. R., Feb 2024, In: Cell Stress and Chaperones. 29, 1, p. 88-96 9 p.

      Research output: Contribution to journal › Editorial

      Open Access
      4 Scopus citations

    • Structural transitions modulate the chaperone activities of Grp94

      Amankwah, Y. S., Fleifil, Y., Unruh, E., Collins, P., Wang, Y., Vitou, K., Bates, A., Obaseki, I., Sugoor, M., Alao, J. P., McCarrick, R. M., Gewirth, D. T., Sahu, I. D., Li, Z., Lorigan, G. A. & Kravats, A. N., Mar 19 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 12, e2309326121.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations

    • Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8 + T cell antitumor immunity

      Li, A., Chang, Y., Song, N. J., Wu, X., Chung, D., Riesenberg, B. P., Velegraki, M., Giuliani, G. D., Das, K., Okimoto, T., Kwon, H., Chakravarthy, K. B., Bolyard, C., Wang, Y., He, K., Gatti-Mays, M., Das, J., Yang, Y., Gewirth, D. T. & Ma, Q. & 2 others, Carbone, D. & Li, Z., Sep 12 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9, e005433.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      28 Scopus citations

    • Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

      Yan, P., Patel, H. J., Sharma, S., Corben, A., Wang, T., Panchal, P., Yang, C., Sun, W., Araujo, T. L., Rodina, A., Joshi, S., Robzyk, K., Gandu, S., White, J. R., de Stanchina, E., Modi, S., Janjigian, Y. Y., Hill, E. G., Liu, B. & Erdjument-Bromage, H. & 6 others, Neubert, T. A., Que, N. L. S., Li, Z., Gewirth, D. T., Taldone, T. & Chiosis, G., Jun 30 2020, In: Cell Reports. 31, 13, 107840.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      56 Scopus citations
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